|Bombyx Mori Extract||Bombyx Mori (Jiang Can) has been utilized in Asia for hundreds of years as a potent aphrodisiac. It is a rare, much sought after silkworm extract used to energize the body and lift sex drive. Bombyx acts as an androgen. STEARATE FREE! Silkworm is also a source of deoxynojirimycin, an alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. The process of achieving male enhancement / penile erection involves the integration of psychological, neurological, and vascular processes that combine to initiatea physiologic response within the penile vasculature. Endothelial-mediated dilation of the arteriolar SM results in increased blood flow into the sinusoids of the corpora cavernosum. The sinusoids subsequent fill while simultaneously relaxing to increase compliance. The filling obstructs the venous outflow from the penis by compressing the veins against the tunica albuginea, resulting in penile erection . Our study supports that penile erection (male enhancement), the most important factor of sexual function, is related to the blood pressure of the corpora cavernosum of the penis. The male rats administered 20% ethanol for 8 weeks had a significantly lower blood pressure in the corpora cavernosum of the penis compared with the normal group. In contrast, the blood pressure of the experimental group, administered SWP after feeding on 20% ethanol, increased to a level similar to that of the normal group. Pupae powder possesses a tonic effect that increases the testosterone level in the serum by 19% after 3-week repeat treatments|
Effects of male silkworm pupa powder on the erectile dysfunction by chronic ethanol consumption in rats:
Erectile dysfunction (ED) is a highly prevalent disorder that affects millions of men worldwide. ED is now considered an early manifestation of atherosclerosis, and consequently, a precursor of systemic vascular disease. This study was designed to investigate the effects of male silkworm pupa powder (SWP) on the levels of nitric oxide synthase (NOS) expression, nitrite, and glutathione (GSH); lipid peroxidation; libido; and erectile response of the corpus cavernosum of the rat penis. We induced ED in the study animals by oral administration of 20% ethanol over 8 weeks. The SWP-treated male rats were divided into 3 groups that were orally administered 200, 400, and 800 mg/kg. The libido of the SWP-administered male rats was higher than that of the ethanol control group. In addition, the erectile response of the corpus cavernosum was restored in males on SWP administration, to a level similar to that of the normal group without ED. The testosterone concentration did not increase significantly. The lipid peroxidation in the corpus cavernosum of the male rats administered SWP decreased significantly. In contrast, compared to the ethanol group, SWP-administered male rats showed increased GSH levels in the corpus cavernosum. The level of nitrite and NOS expression in the corpus cavernosum of SWP-administered male rats increased significantly. These results indicated that SWP effectively restored ethanol-induced ED in male rats.
Read The Korean Association of Lab Animal Science study published on The National Center for Biotechnology Information website
See also Peptidomic Analysis of the Brain and Corpora Cardiaca-Corpora Allata Complex in the Bombyx mori
Xiaoguang Liu, Xia Ning, Yan Zhang, Wenfeng Chen, Zhangwu Zhao, and Qingwen Zhang
Department of Entomology, College of Agriculture and Biotechnology, China Agricultural University, China
Received 24 April 2012; Revised 24 October 2012; Accepted 24 October 2012
Academic Editor: Ayman El-Faham
Copyright © 2012 Xiaoguang Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.